Perinatal Biobank of Research Centre for Natural Sciences in Budapest
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Research Group Publications (43)​
Our Publications on the Cover of Placenta
Research Group Publications
Original Research Papers
1.
N.G. Than, R. Romero, Y. Xu, O. Erez, Z. Xu, G. Bhatti, R. Leavitt, T.H. Chung, H. El-Azzamy, C. LaJeunesse, B. Wang, A. Balogh, G. Szalai, S. Land, Z. Dong, S.S. Hassan, T. Chaiworapongsa, M. Krispin, C.J. Kim, A.L. Tarca, Z. Papp, H. Bohn:
Evolutionary origins of the placental expression of Chromosome 19 cluster galectins and their complex dysregulation in preeclampsia.
Placenta, 35, 855-865, 2014.
Impact factor: 2.710
2.
G. Szalai, Y. Xu, R. Romero, T. Chaiworapongsa, Z. Xu, P.J. Chiang, H. Ahn, B. Sundell, O. Plazyo, Y. Jiang, M. Olive, B. Wang, S.M. Jacques, F. Qureshi, A.L. Tarca, O. Erez, Z. Dong, Z. Papp, S.S. Hassan, E. Hernandez-Andrade, N.G. Than:
In vivo experiments reveal the good, the bad and the ugly faces of sFlt-1 in pregnancy.
PLoS ONE, 9(11), e110867, 1-18, 2014.
Impact factor: 3.234
3.
Sz. Szabo, M. Mody, R. Romero, Y. Xu, K. Karaszi, N. Mihalik, Z. Xu, G. Bhatti, T. Fule, P. Hupuczi, T. Krenacs, J. Rigo Jr., A.L. Tarca, S.S. Hassan, T. Chaiworapongsa, I. Kovalszky, Z. Papp, N.G. Than:
Activation of villous trophoblastic p38 and ERK1/2 signaling pathways in preterm preeclampsia and HELLP syndrome.
Pathology & Oncology Research, 21(3), 659-668, 2015.
Impact factor: 1.940
4.
G. Szalai, R. Romero, T. Chaiworapongsa, Y. Xu, B. Wang, H. Ahn, Z. Xu, P.J. Chiang, B. Sundell, R. Wang, Y. Jiang, O. Plazyo, M. Olive, A.L. Tarca, Z. Dong, F. Qureshi, Z. Papp, S.S. Hassan, E. Hernandez-Andrade, N.G. Than:
Full-length human placental sFlt-1-e15a isoform induces distinct maternal phenotypes of preeclampsia in mice.
PLoS ONE, 10(4), e0119547, 1-42, 2015.
Impact factor: 3.057
5.
S. Mazaki-Tovi, E. Vaisbuch, A.L. Tarca, J.P. Kusanovic, N.G. Than, T. Chaiworapongsa, Z. Dong, S.S. Hassan, R. Romero:
Characterization of visceral and subcutaneous adipose tissue transcriptome and biological pathways in pregnant and non-pregnant women: Evidence for pregnancy-related regional-specific differences in adipose tissue.
PLoS ONE, 10(12), e0143779, 1-35, 2015.
Impact factor: 3.057
7.
U. Krishnamurthy, G. Szalai, Y. Shen, Z. Xu, B.K. Yadav, A.L. Tarca, T. Chaiworapongsa, E. Hernandez-Andrade, N.G. Than, M. Haacke, R. Romero, J. Neelavalli:
Longitudinal changes in placental Magnetic Resonance Imaging relaxation parameter in murine pregnancy: compartmental analysis.
Gynecologic and Obstetric Investigation, 81, 193-201, 2016.
Impact factor: 1.415
8.
B.K. Yadav, J. Neelavalli, U.B. Krishnamurthy, G. Szalai, Y. Shen, NR Nayak, T. Chaiworapongsa, E. Hernandez-Andrade, N.G. Than, E.M. Haacke, R. Romero:
A longitudinal study of placental perfusion using dynamic contrast enhanced Magnetic Resonance Imaging in murine pregnancy.
Placenta, 43, 90-97, 2016.
Impact factor: 2.759
9.
S. Mazaki-Tovi, A.L. Tarca, E. Vaisbuch, J.P. Kusanovic, N.G. Than, T. Chaiworapongsa, Z. Dong, S.S. Hassan, R. Romero:
Characterization of visceral and subcutaneous adipose tissue transcriptome in pregnant women with and without spontaneous labor at term: implication of alternative splicing in the metabolic adaptations of adipose tissue to parturition.
Journal of Perinatal Medicine, 44(7), 813-835, 2016.
Impact factor: 1.577
10.
N. Gomez-Lopez, R. Romero, Y. Xu, O. Plazyo, R. Unkel, N.G. Than, Chaemsaithong,T. Chaiworapongsa, Z. Dong, A.L. Tarca, V.M. Abrahams, L. Yeo, S.S. Hassan:
A role for the inflammasome in spontaneous labor at term with acute histologic chorioamnionitis.
Reproductive Sciences, 24(6): 934-953, 2017.
Impact factor: 2.548
11.
N. Gomez-Lopez, R. Romero, O. Plazyo, Y. Xu, R. Unkel, B. Panaitescu, N.G. Than, T. Chaiworapongsa, Z. Dong, V.M. Abrahams, L. Yeo, S.S. Hassan:
A role for the inflammasome in spontaneous preterm labor with acute histologic chorioamnionitis.
Reproductive Sciences, 24(10): 1382-1401, 2017.
Impact factor: 2.548
12.
H. El-Azzamy, A. Balogh, R. Romero, Y. Xu, C. LaJeunesse, O. Plazyo, Z. Xu, T.G. Price, Z. Dong, A.L. Tarca, Z. Papp, S.S. Hassan, T. Chaiworapongsa, C.J. Kim, N. Gomez-Lopez, N.G. Than:
Characteristic changes in decidual gene expression signature in spontaneous term parturition.
Journal of Pathology and Translational Medicine, 51: 264-283, 2017.
13.
R. Romero, Y. Xu, O. Plazyo, P. Chaemsaithong, T. Chaiworapongsa, R. Unkel, N.G. Than, P.J. Chiang, Z. Dong, Z. Xu, A.L. Tarca, V.M. Abrahams, S.S. Hassan, L. Yeo, N. Gomez-Lopez:
A role for the inflammasome in spontaneous labor at term.
American Journal of Reproductive Immunology, 79(6), e12440, 2018.
Impact factor: 2.745
14.
O. Erez, R. Romero, E. Vaisbuch, J.P. Kusanovic, S. Mazaki-Tovi, T. Chaiworapongsa, F. Gotsch, P. Mittal, S.S. Edwin, C.L. Nhan-Chang, N.G. Than, C.J. Kim, S.K. Kim, L. Yeo, M. Mazor, S.S. Hassan:
The pattern and magnitude of „in vivo thrombin generation” differ in women with preeclampsia and in those with SGA fetuses without preeclampsia.
Journal of Maternal-Fetal & Neonatal Medicine, 31(13): 1671-1680, 2018.
Impact factor: 1.569
15.
O. Erez, R. Romero, E. Vaisbuch, N.G. Than, J.P. Kusanovic, S. Mazaki-Tovi, F. Gotsch, P. Mittal, Z. Dong, T. Chaiworapongsa, C.J. Kim, C.L. Nhan-Chang, S.K. Kim, L. Yeo, M. Mazor, S.S. Hassan:
Tissue factor activity in women with preeclampsia or SGA: a potential explanation for the excessive thrombin generation in these syndromes.
Journal of Maternal-Fetal & Neonatal Medicine, 31(12): 1568-1577, 2018.
Impact factor: 1.569
16.
L. Madar-Shapiro, I. Karady, A. Trahtenherts, A. Syngelaki, R. Akolekar, L. Poon, R. Cohen, A. Sharabi-Nov, B. Huppertz, M. Sammar, K. Juhasz, N.G. Than, Z. Papp, R. Romero, K.H. Nicolaides, H. Meiri:
Predicting the risk to develop preeclampsia in the first trimester combining promoter variant -98A/C of LGALS13 (Placental Protein 13), black ethnicity, previous preeclampsia, obesity and maternal age.
Fetal Diagnosis and Therapy,43(4), 250-265, 2018.
Impact factor: 2.040
17.
N.G. Than, R. Romero, A.L. Tarca, K.A. Kekesi, Y. Xu, Z. Xu, K. Juhasz, G. Bhatti, R.J. Leavitt, Zs. Gelencser, J. Palhalmi, T.H. Chung, B.A. Gyorffy, L. Orosz, A. Demeter, A. Szecsi, E. Hunyadi-Gulyas, Zs. Darula, A. Simor, K. Eder, Sz. Szabo, V. Topping, H. El-Azzamy, C. LaJeunesse, A. Balogh, G. Szalai, S. Land, O. Torok, Z. Dong, I. Kovalszky, A. Falus, H. Meiri, S. Draghici, S.S. Hassan, T. Chaiworapongsa, M. Krispin, M. Knöfler, O. Erez, G.J. Burton, C.J. Kim, G. Juhasz, Z. Papp:
Integrated systems biology approach identifies novel maternal and placental pathways of preeclampsia.
Frontiers in Immunology, 9, 1661, 2018.
Impact factor: 4.716
18.
A. Balogh, E. Karpati, A.E. Schneider, Sz. Hetey, A. Szilagyi, K. Juhasz, G. Laszlo, P. Hupuczi, P. Zavodszky, Z. Papp, J. Matko, N.G. Than:
Sex hormone-binding globulin provides a novel entry pathway for estradiol and influences subsequent signaling in lymphocytes via membrane receptor.
Scientific Reports, 9, 4, 2019.
Impact factor: 3.998
19.
K. Karaszi, Sz. Szabo, K. Juhasz, P. Kiraly, B. Kocsis-Deak, B. Hargitai, T. Krenacs, P. Hupuczi, O. Erez, Z. Papp, I. Kovalszky, N.G. Than:
Increased placental expression of Placental Protein 5 (PP5) / Tissue factor pathway inhibitor-2 (TFPI-2) in women with preeclampsia and HELLP syndrome: Relevance to impaired trophoblast invasion?
Placenta, 76, 30-39, 2019.
Impact factor: 3.177
20.
L. Orosz, G. Orosz, L. Veress, D. Dosa, L. Orosz, I. Arany, A. Fabian, L. Medve, K. Pap, Zs. Karanyi, Z. Toth, R. Poka, N.G Than, O. Torok:
Screening for preeclampsia in the first trimester of pregnancy in routine clinical practice in Hungary.
Journal of Biotechnology, 300, 11-19, 2019.
Impact factor: 3.503
21.
A.L. Tarca, R. Romero, N. Benshalom-Tirosh, N.G. Than, D.W. Gudicha, B. Done, P. Pacora, T. Chaiworapongsa, B. Panaitescu, D. Tirosh, N. Gomez-Lopez, S. Draghici, S.S. Hassan, O. Erez:
The prediction of early preeclampsia: Results from a longitudinal proteomics study.
PLoS ONE, 14, e0217273, 2019
Impact factor: 2.740
22.
N.L. Szenasi, E. Toth, A. Balogh, K. Juhasz, K. Karaszi, O. Ozohanics, Zs. Gelencser, P. Kiraly, B. Hargitai, L. Drahos, P. Hupuczi, I. Kovalszky, Z. Papp, N.G. Than:
Proteomic identification of Membrane-associated Placental Protein 4 (MP4) as perlecan and characterization of its placental expression in normal and pathologic pregnancies.
Peer J, 7: e6982, 2019.
Impact factor: 2.38
23.
A. Balogh, E. Toth, R. Romero, K. Parej, D. Csala, N.L. Szenasi, I. Hajdu, K. Juhasz, A.F. Kovacs, H. Meiri, P. Hupuczi, A.L. Tarca, S.S. Hassan, O. Erez, P. Zavodszky, J. Matko, Z. Papp, S.W. Rossi, S. Hahn, E. Pallinger, N.G. Than:
Placental galectins are key players in regulating the maternal adaptive immune response.
Frontiers in Immunology, 10, 1240, 2019.
Impact factor: 5.085
24.
J. King, M.L. Wilson, Sz. Hetey, P. Kiraly, K. Matsuo, A.V. Castaneda, E. Toth, T. Krenacs, P. Hupuczi,
P. Mhawech-Fauceglia, A. Balogh, A. Szilagyi, J. Matko, Z. Papp, L.D. Roman, V.K. Cortessis, N.G. Than.
Dysregulation of placental functions and immune pathways in complete hydatidiform moles.
International Journal of Molecular Sciences, 20: 4999, 2019.
Impact factor: 4.556
25.
A.L. Tarca, R. Romero, O. Erez, D.W. Gudicha, N.G. Than, N. Benshalom-Tirosh, P. Pacora, C.D. Hsu, T. Chaiworapongsa, S.S. Hassan, N. Gomez-Lopez:
Maternal whole blood mRNA signatures identify women at risk of early preeclampsia: a longitudinal study.
Journal of Maternal-Fetal & Neonatal Medicine, https://doi.org/10.1080/14767058.2019.1685964, January 3 2020
Impact factor: 1.737
26.
A. Szilagyi, Zs. Gelencser, R. Romero, Y. Xu, P. Kiraly, A. Demeter, J. Palhalmi, B.A. Gyorffy, K. Juhasz, P. Hupuczi, K.A. Kekesi, G. Meinhardt, Z. Papp, S. Draghici, O. Erez, A.L. Tarca, M. Knöfler, N.G. Than:
Placenta-specific genes, their regulation during villous trophoblast differentiation and dysregulation in preterm preeclampsia.
International Journal of Molecular Sciences, 21, 628, 2020.
Impact factor: 4.556
28.
G. Meinhardt, S. Haider, V. Kunihs, L. Saleh, J. Pollheimer,C. Fiala, Sz. Hetey, Zs. Feher, A. Szilagyi, N.G. Than, M. Knöfler:
Pivotal role of the transcriptional co-activator YAP in trophoblast stemness of the developing human placenta.
Proc. Natl. Acad. Sci. USA, ;117,13562-13570, 2020.
Impact factor: 9.412
29.
Sz. Szabo, K. Karaszi, R. Romero, E. Toth, A. Szilagyi, Zs. Gelencser, Y. Xu, A. Balogh, G. Szalai, P. Hupuczi, B. Hargitai, T. Krenacs, E. Hunyadi-Gulyas, Zs. Darula, K.A. Kekesi, A.L. Tarca, O. Erez, G. Juhasz, I. Kovalszky, Z. Papp, N.G. Than: Proteomic identification of Placental Protein 1 (PP1), PP8 and PP22 and characterization of their placental expression in normal pregnancies and in preeclamspia.
Placenta, https://doi.org/10.1016/j.placenta.2020.05.013, June 22, 2020.
Impact factor: 3.177
30.
A. Balogh, L. Reiniger, Sz. Hetey, P. Kiraly, E. Toth, K. Karaszi, K. Juhasz, Zs. Gelencser, A. Zvara, A. Szilagyi, L.G. Puskas, J. Matko, Z. Papp, I. Kovalszky, Cs. Juhasz, N.G. Than: Decreased expression of ZNF554 in gliomas is associated with the activation of tumor pathways and shorter patient survival.
International Journal of Molecular Sciences, 21, 5762, 2020.
Impact factor: 4.556
Review Papers
1.
N.G. Than, A. Balogh, R. Romero, E. Karpati, O. Erez, A. Szilagyi, I. Kovalszky, M. Sammar, S. Gizurarson, J. Matko, P. Zavodszky, Z. Papp, H. Meiri:
Placental Protein 13 (PP13) – a placental immunoregulatory galectin protecting pregnancy.
Frontiers in Immunology, invited review, 5, Article 348, 1-25, 2014.
2.
N.G. Than, R. Romero, A. Balogh, E. Karpati, S.A. Mastrolia, O. Staretz-Chacham, S. Hahn, O. Erez, Z. Papp, C.J. Kim: Galectins:
Double-edged swords in the cross-roads of pregnancy complications and female reproductive tract inflammation and neoplasia.
Journal of Pathology and Translational Medicine, invited review, 49, 181-208, 2015.
eBook
Editorial
1.
N.G. Than:
A beágyazódás kimutatása klinikai kémiai módszerekkel. Terhességi tesztek.
In: A várandósgondozás kézikönyve, Ed.: Papp Z., Medicina Könyvkiadó, Chapter 12, 107-114, 2016.
2.
N.G. Than:
A beágyazódás kimutatása klinikai kémiai módszerekkel. Terhességi tesztek.
In: A várandósgondozás kézikönyve, Ed.: Papp Z., Medicina Könyvkiadó, Chapter 12, 107-114, 2016.
HUN-PER Study Publications
Original Research Papers
1.
N.G. Than, R. Romero, A.L. Tarca, K.A. Kekesi, Y. Xu, Z. Xu, K. Juhasz, G. Bhatti, R.J. Leavitt, Zs. Gelencser, J. Palhalmi, T.H. Chung, B.A. Gyorffy, L. Orosz, A. Demeter, A. Szecsi, E. Hunyadi-Gulyas, Zs. Darula, A. Simor, K. Eder, Sz. Szabo, V. Topping, H. El-Azzamy, C. LaJeunesse, A. Balogh, G. Szalai, S. Land, O. Torok, Z. Dong, I. Kovalszky, A. Falus, H. Meiri, S. Draghici, S.S. Hassan, T. Chaiworapongsa, M. Krispin, M. Knöfler, O. Erez, G.J. Burton, C.J. Kim, G. Juhasz, Z. Papp:
Integrated systems biology approach identifies novel maternal and placental pathways of preeclampsia.
Frontiers in Immunology, 9, 1661, 2018.
Impact factor: 4.716
2.
A. Balogh, E. Karpati, A.E. Schneider, Sz. Hetey, A. Szilagyi, K. Juhasz, G. Laszlo, P. Hupuczi, P. Zavodszky, Z. Papp, J. Matko, N.G. Than:
Sex hormone-binding globulin provides a novel entry pathway for estradiol and influences subsequent signaling in lymphocytes via membrane receptor.
Scientific Reports, 9, 4, 2019.
Impact factor: 3.998
3.
K. Karaszi, Sz. Szabo, K. Juhasz, P. Kiraly, B. Kocsis-Deak, B. Hargitai, T. Krenacs, P. Hupuczi, O. Erez, Z. Papp, I. Kovalszky, N.G. Than: Increased placental expression of Placental Protein 5 (PP5) / Tissue factor pathway inhibitor-2 (TFPI-2) in women with preeclampsia and HELLP syndrome: Relevance to impaired trophoblast invasion?
Placenta, 76, 30-39, 2019.
Impact factor: 3.177
4.
L. Orosz, G. Orosz, L. Veress, D. Dosa, L. Orosz, I. Arany, A. Fabian, L. Medve, K. Pap, Zs. Karanyi, Z. Toth, R. Poka, N.G Than, O. Torok: Screening for preeclampsia in the first trimester of pregnancy in routine clinical practice in Hungary.
Journal of Biotechnology, 300, 11-19, 2019.
Impact factor: 3.503
5.
N.L. Szenasi, E. Toth, A. Balogh, K. Juhasz, K. Karaszi, O. Ozohanics, Zs. Gelencser, P. Kiraly, B. Hargitai, L. Drahos, P. Hupuczi, I. Kovalszky, Z. Papp, N.G. Than: Proteomic identification of Membrane-associated Placental Protein 4 (MP4) as perlecan and characterization of its placental expression in normal and pathologic pregnancies.
Peer J, 7: e6982, 2019.
Impact factor: 2.38
6.
A. Balogh, E. Toth, R. Romero, K. Parej, D. Csala, N.L. Szenasi, I. Hajdu, K. Juhasz, A.F. Kovacs, H. Meiri, P. Hupuczi, A.L. Tarca, S.S. Hassan, O. Erez, P. Zavodszky, J. Matko, Z. Papp, S.W. Rossi, S. Hahn, E. Pallinger, N.G. Than:
Placental galectins are key players in regulating the maternal adaptive immune response.
Frontiers in Immunology, 10, 1240, 2019.
Impact factor: 5.085
7.
J. King, M.L. Wilson, Sz. Hetey, P. Kiraly, K. Matsuo, A.V. Castaneda, E. Toth, T. Krenacs, P. Hupuczi,
P. Mhawech-Fauceglia, A. Balogh, A. Szilagyi, J. Matko, Z. Papp, L.D. Roman, V.K. Cortessis, N.G. Than.
Dysregulation of placental functions and immune pathways in complete hydatidiform moles.
International Journal of Molecular Sciences, 20: 4999, 2019.
Impact factor: 4.556
8.
A. Szilagyi, Zs. Gelencser, R. Romero, Y. Xu, P. Kiraly, A. Demeter, J. Palhalmi, B.A. Gyorffy, K. Juhasz, P. Hupuczi, K.A. Kekesi, G. Meinhardt, Z. Papp, S. Draghici, O. Erez, A.L. Tarca, M. Knöfler, N.G. Than:
Placenta-specific genes, their regulation during villous trophoblast differentiation and dysregulation in preterm preeclampsia.
International Journal of Molecular Sciences, 21, 628, 2020.
Impact factor: 4.556
9.
Sz. Szabo, K. Karaszi, R. Romero, E. Toth, A. Szilagyi, Zs. Gelencser, Y. Xu, A. Balogh, G. Szalai, P. Hupuczi, B. Hargitai, T. Krenacs, E. Hunyadi-Gulyas, Zs. Darula, K.A. Kekesi, A.L. Tarca, O. Erez, G. Juhasz, I. Kovalszky, Z. Papp, N.G. Than:
Proteomic identification of Placental Protein 1 (PP1), PP8 and PP22 and characterization of their placental expression in normal pregnancies and in preeclamspia.
Placenta, https://doi.org/10.1016/j.placenta.2020.05.013, June 22, 2020.
Impact factor: 3.177